Concurrent Platform Sessions
FRIDAY, APRIL 5 10:45 am-12:30 pm
Program number is in
bold
above title. The first author is the presenter. Full abstracts can be found online
34
Evolution & Quantitative Genetics II
Co-Moderators: Peter Andolfatto, Princeton University, New Jersey
and Harmit Malik, Fred Hutchinson Cancer Center, Seattle,
Washington
Room: Marriott Ballroom Salon 1, Lobby Level
46
- 10:45
Evolutionary change in fatty acid synthase expression underlies
ecological divergence and reproductive isolation in a pair of Australian
Drosophila species.
Henry Chung
1
,
David Loehlin
1
,
Kathy Vacarro
1
,
Heloise Dufour
1
,
Jocelyn Millar
2
,
Sean Carroll
1
.
1)
HHMI and
Laboratory of Molecular Biology, University of Wisconsin, Madison,
WI; 2) 2Department of Entomology, University of California,
Riverside, CA.
47
- 11:00
Evolution of
miR-92a
underlies natural variation in the naked valley
in
Drosophila melanogaster
.
Saad Arif
1
,
Sophie Murat
2
,
Isabel
Almudi
1
,
Maria Nunes
1
,
Diane Bortolamiol-Becet
3
,
Naomi
McGregor
1
,
James Currie
1
,
Matthew Ronshaugen
4
,
Elio Sucena
5
,
Eric C. Lai
3
,
Christian Schlötterer
2
,
Alistair McGregor
1
.
1)
Oxford
Brookes University, Oxford, United Kingdom; 2) Institute for
Population Genetics, Vetmeduni Vienna, Vienna, Austria; 3) Sloan-
Kettering Institute, New York, NY, USA; 4) Faculty of Life Sciences,
University of Manchester, Manchester, United Kingdom; 5) Instituto
Gulbenkian de Ciência, Oeiras, Portugal.
48
- 11:15
The power of a multivariate approach to genome-wide association
studies.
David Houle
1
,
Jessica Nye
1,2
,
Eladio Marquez
1
,
William
Pitchers
3
,
Alycia Kowalski
3
,
Ian Dworkin
3
.
1)
Dept Biological
Science, Florida State Univ, Tallahassee, FL; 2) Dept. of Genetics,
North Carolina State Univ, Raleigh, NC; 3) Dept. of Zoology, Michigan
State University, Lansing, MI.
49
- 11:30
The severity of a mitochondrial-nuclear incompatibility depends upon
the developmental thermal environment.
Kristi L. Montooth, Luke A.
Hoekstra, Mohammad A. Siddiq.
Dept Biol, Indiana Univ,
Bloomington, IN.
50
- 11:45
A Drosophila Model to Investigate Natural Variation Effect in
Response to Expression of A Human Misfolded Protein.
Bin He
1
,
Michael Ludwig
1
,
Soo-Young Park
2
,
Pengyao Jiang
1
,
Cecelia
Miles
3
,
Levi Barse
1
,
Desiree Dickerson
1
,
Sarah Carl
1
,
Graeme Bell
2
,
Martin Kreitman
1
.
1)
Department of Ecology & Evolution, The
University of Chicago, Chicago, IL; 2) Department of Medicine, The
University of Chicago, Chicago, IL; 3) Biology Department, Augustana
College, Sioux Falls, SD.
51
- 12:00
From missing genotypes to negative epistasis.
Russ Corbett-Detig,
Jun Zhou, Daniel Hartl, Julien Ayroles.
OEB, Harvard University,
Cambridge, MA.
52
- 12:15
Adaptation to hypoxia in experimentally evolved Drosophila
melanogaster: convergent and highly polygenic.
Aashish R. Jha
1,2
,
Christopher D. Brown
2
,
Dan Zhou
3
,
Gabriel H. Haddad
3
,
Kevin P.
White
1,2,4
.
1)
Human Genetics, The University of Chicago, Chicago, IL;
2)
Institute of Genomics and Systems Biology, The University of
Chicago, Chicago, IL; 3) Department of Pediatrics, University of
California an Diego; 4) Ecology and Evolution, The University of
Chicago, Chicago, IL.
Cell Biology & Signal Transduction II
Co-Moderators: Helen McNeil, Mount Sinai Hospital, Toronto, Canada
and Jin Jiang, UTSW, Dallas, Texas
Room: Marriott Ballroom Salon 2, Lobby Level
53
- 10:45
The spatial distribution of tension on E-cadherin in migrating border
cells.
Danfeng Cai
1
,
Li He
2
,
Jessica Sawyer
3
,
Denise Montell
1
.
1)
Department of Biological Chemistry, Johns Hopkins University,
Baltimore, MD; 2) Department of Genetics, Harvard Medical School,
HHMI, Boston, MA; 3) Department of Pharmacology and Cancer
Biology, Duke University School of Medicine, Durham, NC.
54
- 11:00
Real-time analysis of the dynamics of coordinated epithelial
plasticity.
Lara C. Skwarek, David Bilder.
Molecular and Cell
Biology, University of California, Berkeley, Berkeley, CA.
55
- 11:15
Robo2 shapes Slit-dependent muscle repulsion by altering the
association of Slit to tendon cell surface.
Elly Ordan
1
,
Marko
Brankatschk
2
,
Frank Schnorrer
3
,
Talila Volk
1
.
1)
molecular
genetics, Weizmann Institute of Science, Rehovot, Israel; 2) Max
Planck Institute of Molecular Cell Biology and Genetics, Dresden,
Germany; 3) Muscle Dynamics,Max-Planck-Institute for Biochemistry,
Munich,Germany.
56
- 11:30
Regulation of Hippo signaling by EGFR-MAPK signaling through
Ajuba.
Venu Reddy Bommireddy Venkata, Ken Irvine.
Waksman
Institute, Piscataway, NJ.
57
- 11:45
Src controls tumorigenesis through JNK-dependent regulation of the
Hippo pathway.
Masato Enomoto
1
,
Tatsushi Igaki
1,2
.
1)
Division of
Genetics, Kobe University Graduate School of Medicine, Kobe, Japan;
2)
PRESTO, Japan Science and Technology Agency (JST), Saitama,
Japan.
58
- 12:00
The Hippo Pathway targets the Cdh1/fzr inhibitor Rae1 to regulate
mitosis and establish organ size homeostasis.
Maryam Jahanshahi
1
,
Kuangfu Hsiao
2
,
Andreas Jenny
3
,
Cathie Pfleger
1
.
1)
Department of
Oncological Sciences, Mount Sinai School of Medicine, New York,
NY; 2) Fishberg Department of Neuroscience, Mount Sinai School of
Medicine, New York NY; 3) Department of Molecular and
Developmental Biology, Albert Einstein College of Medicine, Bronx
NY.
59
- 12:15
dCORL is required for dSmad2 activation of Ecdysone Receptor
expression in the Drosophila mushroom body.
Stuart J. Newfeld
1
,
Michael Stinchfield
1
,
Kazumichi Shimizu
2
,
Mayu Arase
3
,
Janine
Quijano
1
,
Tetsuro Watabe
3
,
Kohei Miyazono
3
,
Norma T.
Takaesu
1
.
1)
Sch Life Sci, Arizona State Univ, Tempe, AZ; 2) Institute
of Molecular and Cellular Biosciences, University of Tokyo, Tokyo
113-0032,
Japan; 3) Department of Molecular Pathology, University of
Tokyo, Tokyo 113-0033, Japan.
