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Poster Full Abstracts - Cell Death
Poster board number is above title. The first author is the presenter
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suppressed the apoptosis phenotype caused by IAP-antagonist (Hid) overexpression through the eye-specific GMR promoter. We also examined the degree
of IAP-antagonist induction in response to gamma irradiation. This treatment induced Hid expression in cdk7+ imaginal discs, but inactivation of cdk7
almost completely blocked radiation-induced Hid expression. These results indicate that CDK7 has a previously unrecognized role in regulating apoptosis,
independent of its role in cell cycle and general transcription.